Adamax 10 mg Research Peptide

CAS Number: Not formally assigned (research analogue, confirm with batch-specific COA)
Synonyms: Adamax Peptide, Ac-Semax-Adamantyl Analogue, Adamantane-Modified Semax/P21 Hybrid, Ac-MEHFPGPAG-NH₂
Quantity: 10 mg (lyophilised)

Key Features of Adamax 10 mg

Adamax 10 mg is a high-purity synthetic research peptide designed for advanced neurobiological and neuropharmacological studies. Furthermore, every batch undergoes rigorous quality control to ensure consistency and reliability.

• Purity: ≥ 98% (HPLC-verified)
• Identity confirmation: Mass spectrometry (MS) verified
• Endotoxin level: ≤ 5 EU/mg
• Form: Freeze-dried (lyophilised) powder
• Documentation: Certificate of Analysis (COA) supplied with every lot

Adamax Peptide Specifications

Adamax combines the established Semax recognition sequence with structural modifications inspired by Peptide 021 (P21). As a result, researchers can investigate potential improvements in peptide stability and lipophilicity.

• Sequence: Ac-MEHFPGPAG-NH₂
• Length: 9 amino acid residues with terminal adamantyl modification
• Molecular Formula: C₅₀H₆₉N₁₁O₁₁S
• Molecular Weight: 1032.23 g/mol
• Appearance: White to off-white lyophilised powder
• Solubility: Soluble in DMSO and compatible with selected aqueous buffers
• Classification: Synthetic adamantane-modified peptide analogue for laboratory research

What Is Adamax?

Adamax is a designer analogue derived from Semax, an ACTH(4-7) peptide derivative. Additionally, developers incorporated key structural features associated with Peptide 021 (P21), creating a hybrid research peptide with enhanced physicochemical properties.

The design retains the Semax core sequence to preserve its recognition profile. Meanwhile, N-terminal acetylation and C-terminal adamantyl-carboxamide capping help improve resistance to enzymatic degradation and increase lipophilicity.

Adamax Peptide Design and Derivation

Several structural modifications distinguish Adamax from native Semax.

Preserved Semax Recognition Motif

The peptide retains the core sequence Met-Glu-His-Phe-Pro-Gly-Pro. Consequently, researchers can study how additional modifications influence peptide behaviour without altering the primary recognition motif.

Enhanced Stability

N-terminal acetylation helps reduce susceptibility to aminopeptidase degradation. Furthermore, the adamantyl-carboxamide cap may contribute to greater metabolic stability in laboratory models.

Improved Lipophilicity

The Ala-Gly extension and adamantyl modification increase lipophilicity. Therefore, researchers frequently investigate Adamax in studies examining peptide transport and blood-brain barrier interactions.

Synthetic Manufacturing

Manufacturers produce Adamax using controlled synthetic processes to ensure:

• High sequence fidelity
• Controlled purity
• Batch-to-batch reproducibility

As a result, researchers can confidently use it in demanding research environments that require consistent materials.

Adamax Applications in Research

Researchers use Adamax exclusively for laboratory research. In particular, they investigate its properties in:

• Neurotrophic signalling pathway studies
• BDNF and TrkB pathway research
• Neuropeptide stability assessments
• Lipophilicity investigations
• Neuropharmacological screening workflows
• Peptide transport and permeability studies

Reconstitution and Handling Guidelines

To maintain peptide integrity, follow proper handling procedures.

• Reconstitute under sterile and dry conditions.
• Use DMSO or a compatible buffered aqueous system.
• Aliquot after reconstitution to minimise freeze-thaw exposure.
• Store reconstituted solutions at 2-8°C for short-term use.
• Handle promptly because the peptide is hygroscopic.

Storage and Stability

Proper storage helps preserve product quality and performance.

Long-Term Storage

Store Adamax at -20°C in a dry environment protected from light.

Short-Term Storage

Store the peptide at 2-8°C for temporary use.

Additionally, avoid repeated freeze-thaw cycles whenever possible because they may affect peptide integrity over time.

Why Choose Adamax 10 mg?

Adamax offers several advantages for peptide researchers:

• High-purity synthetic Semax/P21 hybrid analogue
• Adamantyl C-terminal capping for enhanced stability
• Increased lipophilicity compared with native Semax
• HPLC-verified purity and MS-confirmed identity
• Full batch traceability with COA included
• Lyophilised format for extended shelf life
• Suitable for advanced neuropeptide research workflows

Intended Use

We supply Adamax 10 mg strictly for laboratory research purposes. It does not have approval for human or veterinary use, and regulatory authorities have not approved it for diagnostic, therapeutic, or medical applications.

Researchers must ensure compliance with all applicable local regulations regarding the import, possession, handling, and use of research peptides.

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