CAS Number: 335591-03-2
Synonyms: Cortagen Peptide, AEDP Tetrapeptide, Neuroregulatory Tetrapeptide
Quantity: 20 mg (lyophilised)
Key Features
- Purity: ≥ 98% (HPLC-verified)
- Endotoxin: ≤ 5 EU/mg
- Form: Freeze-dried (lyophilised) powder
- Documentation: COA supplied with every lot
Peptide Information
- Sequence: Ala-Glu-Asp-Pro (AEDP)
- Length: 4 amino acids
- Molecular Formula: C₁₄H₂₀N₄O₈
- Molecular Weight: 372.33 g/mol
- Classification: Synthetic neuroregulatory peptide for research workflows, including neuronal protection studies, gene-expression assays, peptide characterisation, and structural analysis applications.
Peptide Origin & Derivation
Cortagen is a short neuroregulatory tetrapeptide derived from the HNG (Humanin-Gly) peptide family, a group of naturally occurring mitochondrial-associated peptides known for their cytoprotective and neuroprotective characteristics.
Humanin and related analogues, including HNG, contain several bioactive peptide fragments. Cortagen (AEDP) represents one of the minimal functional motifs identified within these larger peptide structures. Consequently, researchers frequently investigate AEDP motifs in studies involving peptide signalling pathways and neuroregulatory mechanisms.
Key points of derivation:
- Cortagen is a synthetic analogue inspired by the HNG neuroprotective domain
- It reflects a conserved structural motif associated with neuronal survival pathways
In research environments, laboratories produce Cortagen synthetically to maintain:
- High sequence fidelity
- Consistent purity
- Batch-to-batch reproducibility
Additionally, this AEDP tetrapeptide reflects structural elements identified in HNG-derived peptide sequences and broader neurotrophic-like peptide families.
Research Applications & Laboratory Relevance
Researchers continue to study Cortagen because of its compact tetrapeptide structure, analytical consistency, and compatibility with controlled laboratory workflows. Furthermore, scientists commonly use synthetic neuroregulatory peptides in molecular biology studies involving cellular signalling, peptide interaction analysis, and experimental neuronal models.
The lyophilised format also supports long-term storage stability while allowing accurate preparation and handling during laboratory procedures. As a result, many research facilities value Cortagen for peptide characterisation studies, structural analysis workflows, and high-purity experimental systems requiring reproducible synthetic peptide materials.
Storage & Stability
- Long-term: –20 °C, dry and protected from light
- Short-term: Stable at 2–8 °C
- Note: Avoid repeated freeze-thaw cycles
Intended Use
For laboratory research only. This product is not for human or veterinary use. Furthermore, regulatory authorities have not approved Cortagen for diagnostic, therapeutic, or medical applications. Therefore, laboratories should handle this material using appropriate research safety practices.
Why Choose Cortagen 20 mg?
- High-purity synthetic peptide suitable for sensitive neurobiological and molecular systems
- Full batch traceability
- COA included with every lot
- Lyophilised for extended stability and ease of handling
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